Course Objectives

Samples of Course Objectives and Expected Outcomes

PHAR 592:  Clinical Toxicology

After completion of the course, the student will be able to:

Demonstrate a knowledge of the clinical manifestations of intoxications with drugs, chemicals and biological agents in simulated patient cases.

Determine the relevant patient history, physical exam and laboratory data, and their interpretation, needed to evaluate the severity of a poisoning exposure based on patient case scenarios.

Given patient cases, properly assess the severity of poisoning exposures.

Given patient cases, develop triage and treatment plans that include assessment of:

  • WHO the patient/victims of poisoning are or might be;
  • WHAT the patient may have been exposed to;
  • WHAT types of decontamination would be considered in a poisoning patient
  • WHAT specific decontamination recommendations would be made for a specific poisoning patient
  • WHEN the patient was exposed to a toxin;
  • WHERE the patient should be managed (e.g., at home or on-site, in a doctors office, in an emergency department);
  • WHY the patient was exposed to a toxin;

Critically evaluate the toxicology literature regarding patient assessment and management and apply that information to poisoning patient cases.

Organize and present toxicology case studies that identify key components of the cases, identify relevant physical examination or laboratory information for the cases, determine the most appropriate plan for managing those patient cases.

Utilize available resources/references to answer toxicology-related questions.


PHMY 592: Clinical Toxicology

Cardiovascular Drug Overdose:  Beta blockers, calcium channel blockers, and digoxin

GOAL:    Be able to describe the usual or expected symptoms for cardiovascular drug overdose patients and make reasonable treatment recommendations for those patients.

Upon completion of this topic, the student should be able to meet the following objectives.

OBJECTIVES:

  • List the common agents involved in cardiovascular drug overdose;
  • Based on your understanding of the epidemiology of cardiovascular drug overdose, be able to list the agents most likely to result in serious toxicity or death;
  • Be able to list differences between various beta blockers based on the presence of intrinsic sympathomimetic activity, solubility, distribution, cardioselectivity, and membrane stabilizing effect.
  • Be able to utilize your understanding of the differences between various beta blockers in overdose and how those differences are manifested to develop the most appropriate triage and treatment recommendations for simulated poisoning cases;
  • Be able to utilize your understanding of the differences between various calcium channel blockers in overdose and how those differences are manifested to develop the most appropriate triage and treatment recommendations for simulated poisoning cases;
  • Be able to utilize your understanding of digoxin in overdose to develop the most appropriate triage and treatment recommendations for simulated poisoning cases;
  • Be able to develop the most appropriate treatment plan for patients with cardiovascular drug overdose in simulated poisoning patients who have failed first line and second line therapies.

Course Module: Drugs of Abuse

GOAL:  At the end of this lesson, students will be able to successfully identify and manage poisoning/exposure cases involving LSD, DXM, GHB and GBL, bath salts, marijuana and synthetic cannabinoids.

OBJECTIVES:  At the completion of this lecture, students will:

  • Given a simulated patient case, be able to identify patients with LSD, DXM, GHB, bath salts and synthetic cannabinoid exposures based upon history and clinical effects.
  • Given a simulated patient case, be able to develop a reasonable treatment plan for patients with LSD, GHB, bath salts, or synthetic cannabinoid overdose.
  • Be able to describe some of the history of use of these agents.
  • Be able to identify usual complications of overdose of these agents.

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